Phospholipids in Literature and Publications

Here you can find a selection of useful basic literature on phospholipids as well as publications that are  the results of the phospholipid funding. For the latter, please select "PRC-Projects".

You can further narrow down the number of publications by selecting the format of the publication (article, review, poster, ...), the category (parenteral, oral, dermal, ...) and/or the aggregates described in the therein (liposomes, lipid nanoparticles, etc.).

ArticlePhotodynamic drug delivery for cancer therapy: Designing liposomes for light-controlled release and enhanced drug efficacy

Le Clainche T, Abdelhamid AGA, Carigga Gutierrez NM, Jourdain MA, Leo S, Sancey L, Hurbin A, Coll JL, Elena-Herrmann B, Broekgaarden M, 2025, Eur J Pharm Sci 213, 107221

ArticleRapid Release of Doxorubicin from Thermosensitive Liposomes─Contributions of Leakage Versus Unloading

Hummler H, Regenold M, Allen C, Heerklotz H, 2025, J Phys Chem B 129, 7518–7527

ArticlePhotochemical internalization with verteporfin-liposomes enhances oxaliplatin retention and efficacy in models of pancreatic cancer

Carigga Gutierrez NM, Garden L, Le Clainche T, Kadri Dakir M, Johnson-Corrales F, Bohic S, Henry M, Josserand V, Coll JL, Hurbin A, Broekgaarden M, 2025, J Control Release 387, 114201

ArticleDissolution / Permeation of Amorphous Solid Dispersions of Fenofibrate & Hydrogenated Phospholipid – Spontaneous Formation of Colloids: Nanofiltration & Particle Size Analysis

Czajkowski M, Słaba A, Polarczyk A, Bauer-Brandl A, Skupin-Mrugalska P, Brandl M, 2025, Eur J Pharm Sci 212, 107199

ArticleUnderstanding the transport of drugs across biomimetic barriers of various phospholipid compositions using a combined experimental and computational approach

Kabedev A, Tønning MH, Teleki A, Bauer-Brandl A, Jacobsen AC, 2025, Colloids Surf B Biointerfaces 253, 114706

ArticleThe 8th International Symposium on Phospholipids in Pharmaceutical Research – An update on current research in phospholipids presented at the biennial symposium of the Phospholipid Research Center Heidelberg

Drescher S, Blume A, 2025, Eur J Pharm Sci 210, 107126

ArticleSingle-chain bolalipids PC-C24-PC and PC-C32-PC: impact on skin permeation and penetration of caffeine ex vivo, structural organization of the stratum corneum and corneocyte morphology

Abdelrahman N, Schmolz J, Schwarzinger J, Drescher S, Riethmüller C, Dailey LA, Klang V, 2025, Eur J Pharm Sci 212, 107205.

ArticleLocal delivery of lipid-based nanoparticles containing microbial nucleic acid for osteoimmunomodulation

Rahmani NR, Jahanmard F, Hassani Najafabadi A, Flapper J, Dogan O, Khodaei A, Storm G, Croes M, Kruyt MC, Gawlitta D, Weinans H, Mastrobattista E, Amin Yavari S, 2025, Eur J Pharm Sci 208, 107050.

ArticleA step forward on the in vitro and in vivo validation of rifabutin-loaded liposomes for the management of highly virulent MRSA infections

Coelho MP, Pinho JO, Pinto SN, Gaspar MM, 2025, J Control Release 380, 348-361

ArticleDual targeted lipid nanoparticles for enhanced DNA delivery and transfection of breast cancer cells

Lotter C, Stierli MA, Puligilla RD, Huwyler J, 2025, Eur J Pharm Biopharm 209, 114674

ArticleDesign, evaluation, and in vitro-in vivo correlation of self-nanoemulsifying drug delivery systems to improve the oral absorption of exenatide

Venkatasubramanian R, Al-Maghrabi PM, Alavi O, Lind T, Sassene PJ, Kirkensgaard JJK, Mota-Santiago P, Rades T, Müllertz A, 2025, J Control Release 379, 440-451

ArticleAttenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation

Gollowitzer A, Pein H, Rao Z, Waltl L, Bereuter L, Loeser K, Meyer T, Jafari V, Witt F, Winkler R, Su F, Große S, Thürmer M, Grander J, Hotze M, Harder S, Espada L, Magnutzki A, Gstir R, Weinigel C, Rummler S, Bonn G, Pachmayr J, Ermolaeva M, Harayama T, Schlüter H, Kosan C, Heller R, Thedieck K, Schmitt M, Shimizu T, Popp J, Shindou H, Kwiatkowski M, Koeberle A, 2025, Nat Commun 16, 1774

ArticleSilybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

Koeberle SC, Thürmer M, Su F, Werner M, Grander J, Hofer L, Gollowitzer A, Xuan LL, Benscheid FJ, Bonyadi Rad E, Zarrelli A, Di Fabio G, Werz O, Romanucci V, Lupp A, Koeberle A, 2025, Theranostics 15, 2006-2034.

ArticleBiodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: Formulation, in vitro toxicity and in vivo clearance

Al-Jamal WT, Reboredo C, Abdi U, Curci P, Qadadeh R, Alotaibi H, Casettari L, Hatahet T, 2024, Int J Pharm 668, 124963

ArticleLiposomal Formulation of an Organogold Complex Enhancing Its Activity as Antimelanoma Agent—In Vitro and In Vivo Studies

Pinho JO, Coelho M, Pimpão C, Konwar J, Godinho-Santos A, Noiva RM, Thomas SR, Casini A, Soveral G, Gaspar MM, 2024, Pharmaceutics 16, 1566

ArticleComparison of ionizable lipids for lipid nanoparticle mediated DNA delivery

Lotter C, Kuzucu E, Casper J, Alter CL, Puligilla RD, Detampel P, Lopez JS, Ham AS, Huwyler J, 2024, Eur J Pharm Sci 203, 106898

ArticleMelt-extruded formulations of fenofibrate with various grades of hydrogenated phospholipid exhibit promising in-vitro biopharmaceutical behavior

Czajkowski M, Słaba A, Milanowski B, Bauer-Brandl A, Brandl M, Skupin-Mrugalska P, 2024, Eur J Pharm Sci 203, 106936

ArticleSelf-assembling nanoparticles for delivery of miR-603 and miR-221 in glioblastoma as a new strategy to overcome resistance to temozolomide

Abate M, Porru M, Campani V, Leonetti C, Nele V, Di Paola R, De Martino M, Russo M, Tathode M, Cossu AM, Bocchetti M, Angelillo A, Ianniello M, Petrillo N, Savarese G, Monica RD, Chiariotti L, Addeo R, Caraglia M, De Rosa G, Zappavigna S, 2024, J Control Release 377, 458-469

ArticleTripolar Bolalipids as Key Components of Sustained-Release Drug Delivery Systems

Al Yaman K, Al Bardawil S, Ostojic M, Walrant A, Dolé F, Villette S, Lecomte S, Bestel I, Badarau E, 2024, Bioconjug Chem.

ArticleNano Plasma Membrane Vesicle-Lipid Nanoparticle Hybrids for Enhanced Gene Delivery and Expression

Alter CL, Lotter C, Puligilla RD, Bolten JS, Sedzicki J, Marchese J, Schittny V, Rucci F, Beverly M, Palivan CG, Detampel P, Einfalt T, Huwyler J, Advanced Healthcare Materials n/a, 2401888

WILEY Online library

ArticleOptimizing ex vivo penetration tests via quantitative confocal Raman spectroscopy: Impact of incubation time, skin hydration, surfactant treatment and UVA irradiation on caffeine distribution

Steiner K, Hübel P, Srndic A, Klang V, 2024, International Journal of Pharmaceutics, 124932

ArticleLyso-phosphatidylcholine as an interfacial stabilizer for parenteral monoclonal antibody formulations

Papadopoulos E, Arrahmani BC, Beck K, Friess W, 2024, Eur J Pharm Biopharm 204, 114514

ArticleSelf-assembling nanoparticles for miRNA delivery towards precision medicine against melanoma

Nele V, Liguoro D, Campani V, Angelillo A, Frigerio R, Ortolano A, Mancini R, Fattore L, De Rosa G, Ciliberto G, 2024, Journal of Drug Delivery Science and Technology 101, 106169

ArticleEngineering Radiocatalytic Nanoliposomes with Hydrophobic Gold Nanoclusters for Radiotherapy Enhancement

Carigga Gutierrez NM, Clainche TL, Bulin AL, Leo S, Kadri M, Abdelhamid AGA, Pujol-Solé N, Obaid G, Hograindleur MA, Gardette V, Busser B, Motto-Ros V, Josserand V, Henry M, Sancey L, Hurbin A, Elleaume H, Kandiah E, Guével XL, Coll JL, Broekgaarden M, 2024, Adv Mater, e2404605

ArticleInvestigation of keratolytic impact of synthetic bolalipids on skin penetration of a model hydrophilic permeant

Abdelrahman N, Drescher S, Ann Dailey L, Klang V, 2024, Eur J Pharm Biopharm 203, 114433.

ArticleZeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition

Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkäs K, Bindel N, D’Avanzo E, van Roey R, Hajjaj Y, Özel E, Armstark I, Bereuter L, Su F, Grander J, Bonyadi Rad E, Groenewoud A, Engel FB, Bell GW, Henry WS, Angeli JPF, Stemmler MP, Brabletz S, Koeberle A, Brabletz T, 2024, Nat Cell Biol 26, 1470-1481

ArticleIron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors

Su F, Descher H, Bui-Hoang M, Stuppner H, Skvortsova I, Rad EB, Ascher C, Weiss A, Rao Z, Hohloch S, Koeberle SC, Gust R, Koeberle A, 2024, Redox Biol 75, 103257

ArticleTransfer of ANS-Like Drugs from Micellar Drug Delivery Systems to Albumin Is Highly Favorable and Protected from Competition with Surfactant by “Reserved” Binding Sites

Carabadjac I, Vormittag LC, Muszer T, Wuth J, Ulbrich MH, Heerklotz H, 2024, Mol Pharm.

ArticleLiposomal Rifabutin—A Promising Antibiotic Repurposing Strategy against Methicillin-Resistant Staphylococcus aureus Infections

Pinho JO, Ferreira M, Coelho M, Pinto SN, Aguiar SI, Gaspar MM, 2024, Pharmaceuticals 17, 470.

ReviewThe role of phospholipids in drug delivery formulations – Recent advances presented at the Researcher’s Day 2023 Conference of the Phospholipid Research Center Heidelberg

Wibel R, van Hoogevest P, Drescher S, 2024, European Journal of Pharmaceutics and Biopharmaceutics 197, 114215.

ArticleArchaeal ether lipids improve internalization and transfection with mRNA lipid nanoparticles

Sedlmayr VL, Schobesberger S, Spitz S, Ertl P, Wurm DJ, Quehenberger J, Spadiut O, 2024, Eur J Pharm Biopharm 197, 114213.

ArticleEutectic Resolves Lysolipid Paradox in Thermoresponsive Liposomes

Eckhardt D, Semeraro EF, Steigenberger J, Schnur J, Kalie L, Massing U, Pabst G, Heerklotz H, 2024, Mol Pharm 21, 1768-1776.

ArticleDual centrifugation as a novel and efficient method for the preparation of lipodisks

Ali S, Koehler JK, Silva L, Gedda L, Massing U, Edwards K, 2024, International Journal of Pharmaceutics 653, 123894.

ArticleSurfactants for stabilization of dermal emulsions and their skin compatibility under UVA irradiation: Diacyl phospholipids and polysorbate 80 result in high viability rates of primary human skin cells

Steiner K, Josef Schmolz J, Hoang F, Wolf H, Seiser S, Elbe-Bürger A, Klang V, 2024, International Journal of Pharmaceutics 653, 123903.

ArticleSolubility of Poorly Soluble Drugs in Phosphatidylcholine-Based Drug Delivery Systems: Comparison of the Loading Capacity in the Bulk Formulation and Its Dispersed State

Grüne L, Bunjes H, 2024, Pharmaceuticals (Basel) 17.

ArticleInfluence of preparation method and choice of phospholipid on co-amorphization, physical stability, and dissolution behavior of equimolar indomethacin-phospholipid systems – A case study

Khorami K, Müllertz A, Rades T, 2024, Journal of Drug Delivery Science and Technology 93, 105433.

ArticleReducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Sharifi S, Chaudhari P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M, 2024, Nat Commun 15, 1702

ArticleOral Delivery of the Vancomycin Derivative FU002 by a Surface-Modified Liposomal Nanocarrier

Werner J, Umstätter F, Hertlein T, Mühlberg E, Beijer B, Wohlfart S, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P, 2024, Adv Healthc Mater, e2303654.

ArticleDevelopment and optimization of a one step process for the production and sterilization of liposomes using supercritical CO(2)

Penoy N, Delma KL, Homkar N, Karim Sakira A, Egrek S, Sacheli R, Sacré PY, Grignard B, Hayette MP, Somé TI, Semdé R, Evrard B, Piel G, 2024, Int J Pharm 651, 123769

ArticleSupramolecular dye nanoassemblies for advanced diagnostics and therapies

Ramezani P, De Smedt SC, Sauvage F, 2024, Bioeng Transl Med 9, e10652

ArticleImproved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier

Werner J, Umstätter F, Hertlein T, Beijer B, Kleist C, Mühlberg E, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P, 2024, Nanomedicine: Nanotechnology, Biology and Medicine, 102731.

ReviewPreparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation

Koehler JK, Schmager S, Bender V, Steiner D, Massing U, 2023, Pharmaceuticals 16, 1519.

ArticleMonolayer/Bilayer Equilibrium of Phospholipids in Gel or Liquid States: Interfacial Adsorption via Monomer or Liposome Diffusion?

Ullmann K, Fachet L, Nirschl H, Leneweit G, 2023, Gels 9, 803.

ArticleBrain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms of Parkinson’s Disease

Sela M, Poley M, Mora-Raimundo P, Kagan S, Avital A, Kaduri M, Chen G, Adir O, Rozencweig A, Weiss Y, Sade O, Leichtmann-Bardoogo Y, Simchi L, Age-Mizrachi S, Bell B, Yeretz-Peretz Y, Or AZ, Choudhary A, Rosh I, Cordeiro D, Choen-Adiv S, Berdichevsky Y, Ode A, Shklover J, Shainsky-Roitman J, Schroeder JE, Hershkovitz D, Hasson P, Ashkenazi A, Stern S, Laviv T, Ben-Zvi A, Avital A, Ashery U, Maoz BM, Schroeder A, 2023, Adv. Mater., e2304654.

ArticleFeasibility of the preparation of cochleate suspensions from naturally derived phosphatidylserines

Kristensen S, Hassan K, Andersen NS, Steiniger F, Kuntsche J, 2023, Front. Med. Technol. 5, 1241368.

ArticleHydrogenated phospholipid, a promising excipient in amorphous solid dispersions of fenofibrate for oral delivery: Preparation and in-vitro biopharmaceutical characterization

Czajkowski M, Jacobsen AC, Bauer-Brandl A, Brandl M, Skupin-Mrugalska P, 2023. Int. J. Pharm. 644, 123294.

ArticleBragg-Williams Theory for Particles with a Size-Modulating Internal Degree of Freedom

Bossa GV, May S, 2023. Molecules 28, 5060.

ArticleA step forward on the in vitro and in vivo assessment of a novel nanomedicine against melanoma

Pinho JO, Matias M, Godinho-Santos A, Amaral JD, Mendes E, Perry MJ, Francisco AP, Rodrigues CMP, Gaspar MM, 2023. Int. J. Pharm. 640, 123011.

ArticleA mucoadhesive patch loaded with freeze-dried liposomes for the local treatment of oral tumors

Habib L, Alyan M, Ghantous Y, Shklover J, Shainsky J, Abu El-Naaj I, Bianco-Peled H, Schroeder A, 2023. Drug Delivery Transl. Res. 13, 1228-1245.

ReviewFerroptosis-modulating small molecules for targeting drug-resistant cancer: Challenges and opportunities in manipulating redox signaling

Koeberle SC, Kipp AP, Stuppner H, Koeberle A, 2023. Med Res Rev. 1-69.

ArticleA Novel Approach for the Treatment of Aerobic Vaginitis: Azithromycin Liposomes-in-Chitosan Hydrogel

Čačić A, Amidžić Klarić D, Keser S, Radiković M, Rukavina Z, Jøraholmen MW, Uzelac L, Kralj M, Škalko-Basnet N, Šegvić Klarić M, Vanić Ž, 2023. Pharmaceutics 15, 1356.

ArticleInteraction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): a novel approach for stability assessment of oral drug carriers

Bohsen MS, Tychsen ST, Kadhim AAH, Grohganz H, Treusch AH, Brandl M, 2023. Eur. J. Pharm. Sci., 106384.

ArticleEstablishing a simple perfusion cell culture system for light-activated liposomes

Mäki-Mikola E, Lauren P, Uema N, Kikuchi K, Takashima Y, Laaksonen T, Lajunen T, 2023. Sci. Rep. 13, 2050.

ArticleQuantification of particle number concentration in liposomal suspensions by Laser Transmission Spectroscopy (LTS)

Sennato S, Sarra A, Capria CP, Bombelli C, Donati E, Postorino P, Bordi F, 2023. Colloids Surf. B 222, 113137.

ArticleAPPsα rescues CDK5 and GSK3β dysregulation and restores normal spine density in Tau transgenic mice

Baltissen D, Bold CS, Rehra L, Banićević M, Fricke J, Just J, Ludewig S, Buchholz CJ, Korte M, Müller UC, 2023. Front. Cell Neurosci. 17, 1106176.

ArticlePreclinical validation of a new hybrid molecule loaded in liposomes for melanoma management

Pinho JO, Matias M, Marques V, Eleutério C, Fernandes C, Gano L, Amaral JD, Mendes E, Perry MJ, Moreira JN, Storm G, Francisco AP, Rodrigues CMP, Gaspar MM, 2023. Biomed. Pharmacother. 157, 114021.

ArticleExtending the Pseudo-Phase Model of Detergent-Lipid Dispersions by a Detergent-Binding Protein

Vormittag LC, Heerklotz H, 2022. Langmuir, published online.

ArticleFormulating elafibranor and obeticholic acid with phospholipids decreases drug-induced association of SPARC to extracellular vesicles from LX-2 human hepatic stellate cells

Zivko C, Witt F, Koeberle A, Fuhrmann G, Luciani P, 2022. Eur. J. Pharm. Biopharm., published online

ArticleAn innovative one step green supercritical CO(2) process for the production of liposomes co-encapsulating both a hydrophobic and a hydrophilic compound for pulmonary administration

Penoy N, Delma KL, Tonakpon HA, Grignard B, Evrard B, Piel G, 2022, Int J Pharm 627, 122212

ArticleTracking matricellular protein SPARC in extracellular vesicles as a non-destructive method to evaluate lipid-based antifibrotic treatments

Zivko C, Fuhrmann K, Fuhrmann G, Luciani P, 2022. Commun. Biol. 5, 1155.

ArticleQuantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma

Dzhumashev D, Timpanaro A, Ali S, De Micheli AJ, Mamchaoui K, Cascone I, Rössler J, Bernasconi M, 2022, Cancers (Basel) 14

ArticleProbing Neuropeptide Volume Transmission In Vivo by Simultaneous Near-Infrared Light-Triggered Release and Optical Sensing

Xiong H, Lacin E, Ouyang H, Naik A, Xu X, Xie C, Youn J, Wilson BA, Kumar K, Kern T, Aisenberg E, Kircher D, Li X, Zasadzinski JA, Mateo C, Kleinfeld D, Hrabetova S, Slesinger PA, Qin Z, 2022. Angew. Chem. Int. Ed. 61, e202206122.

ArticleCancer immune therapy using engineered ‛tail-flipping’ nanoliposomes targeting alternatively activated macrophages

Kuninty PR, Binnemars-Postma K, Jarray A, Pednekar KP, Heinrich MA, Pijffers HJ, ten Hoopen H, Storm G, van Hoogevest P, den Otter WK, Prakash J, 2022. Nat. Commun. 13, 4548.

ArticleAPPsα Rescues Tau-Induced Synaptic Pathology

Bold CS, Baltissen D, Ludewig S, Back MK, Just J, Kilian L, Erdinger S, Banicevic M, Rehra L, Almouhanna F, Nigri M, Wolfer DP, Spilger R, Rohr K, Kann O, Buchholz CJ, von Engelhardt J, Korte M, Müller UC, 2022. J. Neurosci. 42, 5782-5802.

ArticleMeasuring Thousands of Single-Vesicle Leakage Events Reveals the Mode of Action of Antimicrobial Peptides

Al Nahas K, Fletcher M, Hammond K, Nehls C, Cama J, Ryadnov MG, Keyser UF, 2022. Anal. Chem. 94, 9530-9539.

ArticleImaging, quantitation and kinetic modelling of intravitreal nanomaterials

Sadeghi A, Ruponen M, Puranen J, Cao S, Ridolfo R, Tavakoli S, Toropainen E, Lajunen T, Ranta VP, van Hest J, Urtti A, 2022. Int. J. Pharm. 621, 121800.

Articlenfluence of Oil Polarity and Cosurfactants on the Foamability of Mono- and Diacylphosphatidylcholine Stabilized Emulsions

Bunk M, Daniels R, 2022. Pharmaceutics 14, 1212.

ArticlePI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling

Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A, 2022. Nat. Commun. 13, 2982.

ArticleLiposomal sunitinib for ocular drug delivery: A potential treatment for choroidal neovascularization

Tavakoli S, Puranen J, Bahrpeyma S, Lautala VE, Karumo S, Lajunen T, Del Amo EM, Ruponen M, Urtti A, 2022. Int. J. Pharm. 620, 121725.

ArticleInternalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels

Beekers I, Langeveld SAG, Meijlink B, van der Steen AFW, de Jong N, Verweij MD, Kooiman K, 2022. J. Controlled Release 347, 460-475.

ArticleGenerating Large Numbers of Pancreatic Microtumors on Alginate-Gelatin Hydrogels for Quantitative Imaging of Tumor Growth and Photodynamic Therapy Optimization

Carigga Gutierrez NM, Le Clainche T, Coll JL, Sancey L, Broekgaarden M, 2022. Methods Mol. Biol. 2451, 91-105.

ArticleSynthetic cells with self-activating optogenetic proteins communicate with natural cells

Adir O, Albalak MR, Abel R, Weiss LE, Chen G, Gruber A, Staufer O, Kurman Y, Kaminer I, Shklover J, Shainsky-Roitman J, Platzman I, Gepstein L, Shechtman Y, Horwitz BA, Schroeder A, 2022. Nat. Commun. 13, 2328.

ArticleLung targeted liposomes for treating ARDS

Arber Raviv S, Alyan M, Egorov E, Zano A, Harush MY, Pieters C, Korach-Rechtman H, Saadya A, Kaneti G, Nudelman I, Farkash S, Flikshtain OD, Mekies LN, Koren L, Gal Y, Dor E, Shainsky J, Shklover J, Adir Y, Schroeder A, 2022. J. Controlled Release 346, 421-433.

ArticleNanoparticles Accumulate in the Female Reproductive System during Ovulation Affecting Cancer Treatment and Fertility

Poley M, Mora-Raimundo P, Shammai Y, Kaduri M, Koren L, Adir O, Shklover J, Shainsky-Roitman J, Ramishetti S, Man F, de Rosales RTM, Zinger A, Peer D, Ben-Aharon I, Schroeder A, 2022. ACS Nano 16, 5246-5257.

ArticleIncorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses

Nijen Twilhaar MK, Czentner L, Bouma RG, Olesek K, Grabowska J, Wang AZ, Affandi AJ, Belt SC, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan JMM, 2022. Front. Immunol. 13, 842241.

ArticleIncorporation of phosphatidylserine improves efficiency of lipid based gene delivery systems

Lotter C, Alter CL, Bolten JS, Detampel P, Palivan CG, Einfalt T, Huwyler J, 2022. Eur. J. Pharm. Biopharm. 172, 134-143.

ArticleImpact of Linker Modification and PEGylation of Vancomycin Conjugates on Structure-Activity Relationships and Pharmacokinetics

Umstätter F, Werner J, Zerlin L, Mühlberg E, Kleist C, Klika KD, Hertlein T, Beijer B, Domhan C, Zimmermann S, Ohlsen K, Haberkorn U, Mier W, Uhl P, 2022. Pharmaceuticals 15, 159.

ArticleTheranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy

Langeveld SAG, Meijlink B, Beekers I, Olthof M, van der Steen AFW, de Jong N, Kooiman K, 2022. Pharmaceutics 14, 311.

ArticleParticle Engineering of Innovative Nanoemulsion Designs to Modify the Accumulation in Female Sex Organs by Particle Size and Surface Charge

Busmann EF, Lucas H, 2022. Pharmaceutics 14, 301.

ArticleOptimizing the Pharmacological and Optical Dosimetry for Photodynamic Therapy with Methylene Blue and Nanoliposomal Benzoporphyrin on Pancreatic Cancer Spheroids

Le Clainche T, Carigga Gutierrez NM, Pujol-Solé N, Coll J-L, Broekgaarden M, 2022 . Onco 2, 19-33.

ArticleQuercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment

Ferreira-Silva M, Faria-Silva C, Carvalheiro MC, Simões S, Marinho HS, Marcelino P, Campos MC, Metselaar JM, Fernandes E, Baptista PV, Fernandes AR, Corvo ML, 2022. Pharmaceutics 14, 194.

ArticleCerosomes as skin repairing agent: Mode of action studies with a model stratum corneum layer at liquid/air and liquid/solid interfaces

Strati F, Mukhina T, Neubert RHH, Opalka L, Hause G, Schmelzer CEH, Menzel M, Brezesinski G, 2022. BBA Advances 2, 100039.

ArticleLiposomal Encapsulation Increases the Efficacy of Azithromycin against Chlamydia trachomatis

Bogdanov A, Janovák L, Vraneš J, Meštrović T, Ljubin-Sternak S, Cseh Z, Endrész V, Burián K, Vanić Ž, Virok DP, 2021, Pharmaceutics 14, 36.

ArticleLecithin-based nanoemulsions of traditional herbal wound healing agents and their effect on human skin cells

Vater C, Bosch L, Mitter A, Gols T, Seiser S, Heiss E, Elbe-Burger A, Wirth M, Valenta C, Klang V, 2022. Eur. J. Pharm. Biopharm. 170, 1-9.

ArticleLyophilization stabilizes clinical-stage core-crosslinked polymeric micelles to overcome cold chain supply challenges

Ojha T, Hu Q, Colombo C, Wit J, van Geijn M, van Steenbergen MJ, Bagheri M, Königs-Werner H, Buhl EM, Bansal R, Shi Y, Hennink WE, Storm G, Rijcken CJF, Lammers T, 2021, Biotechnol J 16, e2000212

ArticleTargeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases

Kaduri M, Sela M, Kagan S, Poley M, Abumanhal-Masarweh H, Mora-Raimundo P, Ouro A, Dahan N, Hershkovitz D, Shklover J, Shainsky-Roitman J, Buganim Y, Schroeder A, 2021. Sci. Adv. 7, eabj5435.

ArticleOvarian Accumulation of Nanoemulsions: Impact of Mice Age and Particle Size

Busmann EF, Kollan J, Mäder K, Lucas H, 2021. Int. J. Mol. Sci. 22, 8283.

ArticleCD169 Defines Activated CD14(+) Monocytes With Enhanced CD8(+) T Cell Activation Capacity

Affandi AJ, Olesek K, Grabowska J, Nijen Twilhaar MK, Rodríguez E, Saris A, Zwart ES, Nossent EJ, Kalay H, de Kok M, Kazemier G, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Garcia-Vallejo JJ, Storm G, van Kooyk Y, den Haan JMM, 2021. Front. Immunol. 12, 697840.

ArticleIncorporation of Molecular Reorientation into Modeling Surface Pressure-Area Isotherms of Langmuir Monolayers

Agudelo J, Bossa GV, May S, 2021. Molecules 26, 4372.

ArticleRifampicin-Liposomes for Mycobacterium abscessus Infection Treatment: Intracellular Uptake and Antibacterial Activity Evaluation

Rinaldi F, Hanieh PN, Sennato S, De Santis F, Forte J, Fraziano M, Casciardi S, Marianecci C, Bordi F, Carafa M, 2021, Pharmaceutics 13

ArticleMembrane-water partitioning – Tackling the challenges of poorly soluble drugs using chaotropic co-solvents

Nasswetter LC, Fischer M, Scheidt HA, Heerklotz H, 2021. Biophys. Chem. 277, 106654.

ArticleMimicking Pathogens to Augment the Potency of Liposomal Cancer Vaccines

Nijen Twilhaar MK, Czentner L, van Nostrum CF, Storm G, den Haan JMM, 2021. Pharmaceutics 13, 954.

ArticlePhospholipid-coated targeted microbubbles for ultrasound molecular imaging and therapy

Langeveld SAG, Meijlink B, Kooiman K, 2021. Curr. Opinion Chem. Biol. 63, 171-179.

ArticleHow to Achieve High Encapsulation Efficiencies for Macromolecular and Sensitive APIs in Liposomes

Ullmann K, Leneweit G, Nirschl H, 2021. Pharmaceutics 13, 691.

ArticleEncapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions

Hettich BF, Bader JJ, Leroux JC, 2021. Adv. Healthc. Mater., e2100047.

ReviewLiposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance

Ferreira M, Ogren M, Dias JNR, Silva M, Gil S, Tavares L, Aires-da-Silva F, Gaspar MM, Aguiar SI, 2021. Molecules 26, 2047.

ReviewLiver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices

Zivko C, Fuhrmann G, Luciani P, 2021. Biochim. Biophys. Acta, Gen. Subj. 1865, 129559.

ReviewLiposomal Nanosystems in Rheumatoid Arthritis

Ferreira-Silva M, Faria-Silva C, Viana Baptista P, Fernandes E, Ramos Fernandes A, Corvo ML, 2021. Pharmaceutics 13, 454.

Article, Clinical TrialChanges in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy

Vater C, Apanovic A, Riethmüller C, Litschauer B, Wolzt M, Valenta C, Klang V, 2021. Pharmaceutics 13, 436.

ArticleLiposome induction of CD8(+) T cell responses depends on CD169(+) macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion

Grabowska J, Affandi AJ, van Dinther D, Nijen Twilhaar MK, Olesek K, Hoogterp L, Ambrosini M, Heijnen DAM, Klaase L, Hidalgo A, Asano K, Crocker PR, Storm G, van Kooyk Y, den Haan JMM, 2021. J. Controlled Release 331, 309-320.