Here you can find a selection of useful basic literature on phospholipids as well as publications that are the results of the funded projects. For the latter, please select "PRC-Projects".
You can further narrow down the number of publications by selecting the format of the publication (article, review, poster, ...), the category (parenteral, oral, dermal, ...) and/or the aggregates described in the therein (liposomes, lipid nanoparticles, etc.).
ArticleGenerating Large Numbers of Pancreatic Microtumors on Alginate-Gelatin Hydrogels for Quantitative Imaging of Tumor Growth and Photodynamic Therapy Optimization
Carigga Gutierrez NM, Le Clainche T, Coll JL, Sancey L, Broekgaarden M, 2022. Methods Mol. Biol. 2451, 91-105.
| PubMed |
ArticleIncorporation of phosphatidylserine improves efficiency of lipid based gene delivery systems
Lotter C, Alter CL, Bolten JS, Detampel P, Palivan CG, Einfalt T, Huwyler J, 2022. Eur. J. Pharm. Biopharm. 172, 134-143.
| PubMed |
ArticleTargeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases
Kaduri M, Sela M, Kagan S, Poley M, Abumanhal-Masarweh H, Mora-Raimundo P, Ouro A, Dahan N, Hershkovitz D, Shklover J, Shainsky-Roitman J, Buganim Y, Schroeder A, 2021. Sci. Adv. 7, eabj5435.
| PubMed |
ReviewLiposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance
Ferreira M, Ogren M, Dias JNR, Silva M, Gil S, Tavares L, Aires-da-Silva F, Gaspar MM, Aguiar SI, 2021. Molecules 26, 2047.
| PubMed |
ArticleTowards the Development of Long Circulating Phosphatidylserine (PS)- and Phosphatidylglycerol (PG)-Enriched Anti-Inflammatory Liposomes: Is PEGylation Effective?
Klein ME, Rieckmann M, Sedding D, Hause G, Meister A, Mäder K, Lucas H, 2021. Pharmaceutics 13, 282.
| PubMed |
ReviewThe Use of Phospholipids to make Pharmaceutical Form Line Extensions
van Hoogevest P, Tiemessen H, Metselaar JM, Drescher S, Fahr A, 2021. Eur. J. Lipid Sci. Technol., 2000297.
| Wiley |
ReviewThe Phospholipid Research Center: Current Research in Phospholipids and their Use in Drug Delivery
Drescher S, van Hoogevest P, 2020. Pharmaceutics 12, 1235.
| PubMed |
ArticleAnalytical profiling and stability evaluation of liposomal drug delivery systems: a rapid UHPLC-CAD-based approach for phospholipids in research and quality control
Weber F, Rahnfeld L, Luciani P, 2020. Talanta 220, 121320.
| PubMed |
ArticleOptimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages
Nijen Twilhaar MK, Czentner L, Grabowska J, Affandi AJ, Lau CYJ, Olesek K, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan J, 2020. Pharmaceutics 12, 1138.
| PubMed |
ArticleSelective tumor antigen vaccine delivery to human CD169(+) antigen-presenting cells using ganglioside-liposomes
Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E, Mulder PPG, Pijffers HJ, Ambrosini M, Kalay H, O’Toole T, Zwart ES, Kazemier G, Nazmi K, Bikker FJ, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Storm G, van Kooyk Y, den Haan JMM, 2020. Proc. Natl. Acad. Sci. U. S. A. 117, 27528-27539.
| PubMed |
ArticleSpontaneous In Situ Formation of Liposomes from Inert Porous Microparticles for Oral Drug Delivery
Farzan M, Quebatte G, Strittmatter K, Hilty FM, Schoelkopf J, Huwyler J, Puchkov M, 2020. Pharmaceutics 12, 777.
| PubMed |
ArticleLight-Activated Liposomes Coated with Hyaluronic Acid as a Potential Drug Delivery System
Kari OK, Tavakoli S, Parkkila P, Baan S, Savolainen R, Ruoslahti T, Johansson NG, Ndika J, Alenius H, Viitala T, Urtti A, Lajunen T, 2020. Pharmaceutics 12, 763.
| PubMed |
Article, Clinical TrialHybrid lipid self-assembling nanoparticles for brain delivery of microRNA
Campani V, Zappavigna S, Scotti L, Abate M, Porru M, Leonetti C, Caraglia M, De Rosa G, 2020. Int. J. Pharm. 588, 119693.
| PubMed |
ArticlePhosphatidylserine (PS)- and phosphatidylglycerol-(PG)-enriched mixed micelles (MM): a new nano-drug delivery system with anti-inflammatory potential?
Klein ME, Rieckmann M, Lucas H, Meister A, Loppnow H, Mäder K, 2020. Eur. J. Pharm. Sci., 105451.
| PubMed |
ArticleSelf-dispersing formulations for the delivery of poorly soluble drugs – Miscibility of phosphatidylcholines with oils and fats
Grüne L, Bunjes H, 2020. Eur. J. Pharm. Biopharm. 151, 209-219.
| PubMed |
ReviewNon‐Aqueous Phospholipid Concentrates for Increasing the Bioavailability of Poorly Soluble Compounds
van Hoogevest P, 2020. Eur. J. Lipid Sci. Technol. 122, 1900411.
| Wiley |
ReviewUltrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery
Kooiman K, Roovers S, Langeveld SAG, Kleven RT, Dewitte H, O’Reilly MA, Escoffre JM, Bouakaz A, Verweij MD, Hynynen K, Lentacker I, Stride E, Holland CK, 2020. Ultrasound Med. Biol. 46, 1296-1325.
| PubMed |
ArticleThe role of liposomes in clinical nanomedicine development. What now? Now what?
Crommelin DJA, van Hoogevest P, Storm G, 2020. J. Controlled Release 318, 256-263.
| PubMed |
ArticleUltrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization
de Matos MBC, Deckers R, van Elburg B, Lajoinie G, de Miranda BS, Versluis M, Schiffelers R, Kok RJ, 2019. Front. Pharmacol. 10, 1463.
| PubMed |
ArticleBolalipid-Doped Liposomes: Can Bolalipids Increase the Integrity of Liposomes Exposed to Gastrointestinal Fluids?
Müller S, Gruhle K, Meister A, Hause G, Drescher S, 2019. Pharmaceutics 11, 646.
| PubMed |
ArticleCollagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors
Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, Noor N, Krinsky N, Simon A, Gibori H, Krayem M, Mumblat Y, Kasten S, Ofir S, Fridman E, Milman N, Lubtow MM, Liba L, Shklover J, Shainsky-Roitman J, Binenbaum Y, Hershkovitz D, Gil Z, Dvir T, Luxenhofer R, Satchi-Fainaro R, Schroeder A, 2019. ACS Nano 13, 11008-11021.
| PubMed |
ArticleEvaluation of Hydrogenated Soybean Phosphatidylcholine Matrices Prepared by Hot Melt Extrusion for Oral Controlled Delivery of Water-Soluble Drugs
Kolbina M, Schulte A, van Hoogevest P, Körber M, Bodmeier R, 2019. AAPS PharmSciTech 20, 159.
| PubMed |
ArticleSodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin
Abumanhal-Masarweh H, Koren L, Zinger A, Yaari Z, Krinsky N, Kaneti G, Dahan N, Lupu-Haber Y, Suss-Toby E, Weiss-Messer E, Schlesinger-Laufer M, Shainsky-Roitman J, Schroeder A, 2019. J. Controlled Release 296, 1-13.
| PubMed |
Article, Clinical TrialNLC versus nanoemulsions: Effect on physiological skin parameters during regular in vivo application and impact on drug penetration
Wolf M, Klang V, Stojcic T, Fuchs C, Wolzt M, Valenta C, 2018. Int. J. Pharm. 549, 343-351.
| PubMed |
ArticleThermosensitive liposomes for triggered release of cytotoxic proteins
de Matos MBC, Beztsinna N, Heyder C, Fens M, Mastrobattista E, Schiffelers RM, Leneweit G, Kok RJ, 2018. Eur. J. Pharm. Biopharm. 132, 211-221.
| PubMed |
ArticleMonoacyl-phosphatidylcholine based drug delivery systems for lipophilic drugs: Nanostructured lipid carriers vs. nano-sized emulsions
Wolf M, Reiter F, Heuser T, Kotisch H, Klang V, Valenta C, 2018. J. Drug Delivery Sci. Technol. 46, 490-497.
| Google Scholar |
ArticleRock the nucleus: significantly enhanced nuclear membrane permeability and gene transfection by plasmonic nanobubble induced nanomechanical transduction
Li X, Kang P, Chen Z, Lal S, Zhang L, Gassensmith JJ, Qin Z, 2018. Chem. Commun. 54, 2479-2482.
| PubMed |
ArticleTargeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer
Binnemars-Postma KA, Bansal R, Storm G, Prakash J, 2018. FASEB J. 32, 969-978.
| PubMed |
Special IssueUse of phospholipids in oral drug delivery
Martin Brandl, Alfred Fahr, Peter van Hoogevest, Sophia Yui Kau Fong, Special Issue Eur. J. Pharm. Sci. 2017, Volume 108, Pages 1-118.
| ScienceDirect |
ArticleSaturated phosphatidylcholine as matrix former for oral extended release dosage forms
Kolbina M, Bodmeier R, Körber M, 2017. Eur. J. Pharm. Sci. 108, 86-92.
| PubMed |
ArticleNanomedicine Strategies to Target Tumor-Associated Macrophages
Binnemars-Postma KA, Storm G, Prakash J, 2017. Int. J. Mol. Sci. 18, 979.
| PubMed |
Special IssuePhospholipids in pharmaceutical research
Peter van Hoogevest, 2014. Special Issue, Eur. J. Lipid Sci. Technol. 116, 1087-1255.
| Wiley |
ReviewTherapeutic liposomal dry powder inhalation aerosols for targeted lung delivery
Willis L, Hayes D, Jr., Mansour HM, 2012. Lung 190, 251-262.
| PubMed |
ReviewLiposomal systems as drug delivery vehicles for dermal and transdermal applications
Pierre MBR, dos Santos Miranda Costa I, 2011. Archives of Dermatological Research 303, 607.
| Springer |
ReviewRole of phospholipids in the oral and parenteral delivery of poorly water soluble drugs
van Hoogevest P, Liu X, Fahr A, Leigh MLS, 2011. J. Drug Delivery Sci. Technol. 21, 5-16.
| Sciencedirect |
ReviewLiposomes as drug delivery systems for the treatment of TB
Pinheiro M, Lucio M, Lima JLFC, Reis S, 2011. Nanomedicine (London, U. K.) 6, 1413-1428.
| PubMed |
ReviewPhospholipids and lipid-based formulations in oral drug delivery
Fricker G, Kromp T, Wendel A, Blume A, Zirkel J, Rebmann H, Setzer C, Quinkert R-O, Martin F, Müller-Goymann CC, 2010. Pharm. Res. 27, 1469-1486.
| PubMed |
ReviewTransfer of lipophilic drugs between liposomal membranes and biological interfaces: Consequences for drug delivery
Fahr A, van Hoogevest P, May S, Bergstrand N, Leigh MLS, 2005. Eur. J. Pharm. Sci. 26, 251-265.
| PubMed |
Book and Book ChapterLong Circulating Liposomes: Old Drugs, New Therapeutics: Making Old Drugs New Therapeutics
Woodle MC, Storm G, 1997. Springer.
| Google Scholar |