CRS 2024 Annual Meeting and Exposition

The 2024 Annual Meeting and Exposition of the Controlled Release Society (CRS) will take place on July 08-12, 2024, in Bologna, Italy.

This year, the conference theme is “Integrating Delivery Science across disciplines”, building on the notion that daily activities rely on the continuous integration of multiple knowledge domains and expertise, from pharmaceutical sciences to engineering, from biotechnology to materials science and chemistry, from molecular imaging to clinical translation, with the ultimate objective of benefiting patients and their families.

For more information, please visit the Conference homepage.

Workshop organized by the Phospholipid Research Center

The Phospholipid Research Center will organize a half-day workshop on the important topic of phospholipids.

Organizer

  • Prof. Dr. Paola Luciani (University Bern, Switzerland)
  • Priv.-Doz. Dr. habil. Simon Drescher (Phospholipid Research Center Heidelberg, Germany)

Summary

Goals of the workshop are to inform on the basic properties of phospholipid excipients, including physical chemistry aspects, and their use in pharmaceutical technology. Target group are interested academic researchers as well as pharmaceutical industrial scientists interested in the use of phospholipid excipients. The audience will be informed on selection and use of phospholipids in obtaining optimal liposomal dosage forms for various applications, including parenteral depot formulations and hot-melt extrusion for oral formulations of poorly soluble drugs, and on the latest advances on phospholipids in gene replacement therapy, infectious diseases, targeted therapy, nanobubble ablation in ophthalmology.

Learning Objectives

To demonstrate the correlation between the physicochemical properties of the used phospholipids and phospholipid-based dosage forms and the performance of the drug substance (toxicity, efficacy, bioavailability and pharmacokinetics) with mentioned delivery systems.

The audience will be informed on the latest advances in this phospholipid area in two sessions: The first session is a more general session on the use of phospholipids as excipients, whereas the second session will focus on application examples from liposomes and lipid nanoparticles (LNPs).

First Session - Phospholipids as excipients

  • Priv.-Doz. Dr. habil. Simon Drescher (PRC Heidelberg, Germany): The Phospholipid Research Center Heidelberg: An introduction and ongoing research projects
  • Priv.-Doz. Dr. Peter van Hoogevest (University Basel, Switzerland; Pharmanovation Rheinfelden, Germany): An Introduction on the use and properties of phospholipid excipients
  • Dr. Paulina Skupin-Mrugalska (Poznan University of Medical Sciences, Poland): Phospholipids as excipients in (amorphous) solid dispersions
  • Prof. Dr. Paola Luciani (University Bern, Switzerland) Phospholipids in parenteral depot formulations: recent advances, current challenges, and future opportunities

Second Session - Liposomes and LNPs

  • Dr. Mans Broekgaarden (University Grenoble, France): Radiocontrolled drug delivery with high-Z element-functionalized liposomes
  • Prof. Dr. Davide Brambilla (University Montréal, Canada): Phospholipid nanoparticles for lipase deficiency gene replacement therapy
  • Dr. Manuela Gaspar (University of Lisbon, Portugal): Advancing the treatment of infectious diseases – the key role of liposomes as delivery systems
  • Prof. Dr. Félix Sauvage (Ghent University, Belgium): Photo-induced destruction of vitreous opacities using nanobubbles generating liposomes