Webinar May 2023 – Dr. Wang
On Friday, May 05, 2023, an online seminar on "Liposomal phospholipid bilayer facilitates DHA utilization in atherosclerosis" was held at 3.30 p.m. (CEST).
The speaker was Assist. Professor Dr. Jiong-Wei Wang from the National University of Singapore.
Liposomes are bilayer lipid membrane nanoparticles comprising phospholipids with a hydrophobic tail and a hydrophilic head to form an aqueous core and a lipophilic bilayer. This unique structure enables liposomes to deliver both hydrophilic and hydrophobic drugs. In our recent study, we employed liposomal phospholipid bilayer to solubilize an omega-3 fatty acid, docosahexaenoic acid (DHA), for intravenous application. While DHA has been suggested to benefit patients with cardiovascular disease, its anti-atherosclerosis effects have been controversial likely due to variations in bioavailability after oral intake. Hereby we aimed to fully exploit the potential therapeutic effects of DHA on atherosclerosis by intravenous administration of liposomal DHA.
In this webinar, latest research on this topic will be presented. More specifically, the protective effects of liposomal phospholipids on DHA stability and the therapeutic mechanisms of liposomal DHA for the treatment of atherosclerosis from a biological perspective will be discussed.