Phospholipids in Literature and Publications

Here you can find a selection of useful basic literature on phospholipids as well as publications that are  the results of the phospholipid funding. For the latter, please select "PRC-Projects".

You can further narrow down the number of publications by selecting the format of the publication (article, review, poster, ...), the category (parenteral, oral, dermal, ...) and/or the aggregates described in the therein (liposomes, lipid nanoparticles, etc.).

ArticleLocal delivery of lipid-based nanoparticles containing microbial nucleic acid for osteoimmunomodulation

Rahmani NR, Jahanmard F, Hassani Najafabadi A, Flapper J, Dogan O, Khodaei A, Storm G, Croes M, Kruyt MC, Gawlitta D, Weinans H, Mastrobattista E, Amin Yavari S, 2025, Eur J Pharm Sci 208, 107050.

ArticleA step forward on the in vitro and in vivo validation of rifabutin-loaded liposomes for the management of highly virulent MRSA infections

Coelho MP, Pinho JO, Pinto SN, Gaspar MM, 2025, J Control Release 380, 348-361

ArticleAttenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation

Gollowitzer A, Pein H, Rao Z, Waltl L, Bereuter L, Loeser K, Meyer T, Jafari V, Witt F, Winkler R, Su F, Große S, Thürmer M, Grander J, Hotze M, Harder S, Espada L, Magnutzki A, Gstir R, Weinigel C, Rummler S, Bonn G, Pachmayr J, Ermolaeva M, Harayama T, Schlüter H, Kosan C, Heller R, Thedieck K, Schmitt M, Shimizu T, Popp J, Shindou H, Kwiatkowski M, Koeberle A, 2025, Nat Commun 16, 1774

ArticleSilybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

Koeberle SC, Thürmer M, Su F, Werner M, Grander J, Hofer L, Gollowitzer A, Xuan LL, Benscheid FJ, Bonyadi Rad E, Zarrelli A, Di Fabio G, Werz O, Romanucci V, Lupp A, Koeberle A, 2025, Theranostics 15, 2006-2034.

ArticleBiodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: Formulation, in vitro toxicity and in vivo clearance

Al-Jamal WT, Reboredo C, Abdi U, Curci P, Qadadeh R, Alotaibi H, Casettari L, Hatahet T, 2024, Int J Pharm 668, 124963

ArticleLiposomal Formulation of an Organogold Complex Enhancing Its Activity as Antimelanoma Agent—In Vitro and In Vivo Studies

Pinho JO, Coelho M, Pimpão C, Konwar J, Godinho-Santos A, Noiva RM, Thomas SR, Casini A, Soveral G, Gaspar MM, 2024, Pharmaceutics 16, 1566

ArticleEngineering Radiocatalytic Nanoliposomes with Hydrophobic Gold Nanoclusters for Radiotherapy Enhancement

Carigga Gutierrez NM, Clainche TL, Bulin AL, Leo S, Kadri M, Abdelhamid AGA, Pujol-Solé N, Obaid G, Hograindleur MA, Gardette V, Busser B, Motto-Ros V, Josserand V, Henry M, Sancey L, Hurbin A, Elleaume H, Kandiah E, Guével XL, Coll JL, Broekgaarden M, 2024, Adv Mater, e2404605

ArticleZeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition

Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkäs K, Bindel N, D’Avanzo E, van Roey R, Hajjaj Y, Özel E, Armstark I, Bereuter L, Su F, Grander J, Bonyadi Rad E, Groenewoud A, Engel FB, Bell GW, Henry WS, Angeli JPF, Stemmler MP, Brabletz S, Koeberle A, Brabletz T, 2024, Nat Cell Biol 26, 1470-1481

ArticleIron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors

Su F, Descher H, Bui-Hoang M, Stuppner H, Skvortsova I, Rad EB, Ascher C, Weiss A, Rao Z, Hohloch S, Koeberle SC, Gust R, Koeberle A, 2024, Redox Biol 75, 103257

ArticleLiposomal Rifabutin—A Promising Antibiotic Repurposing Strategy against Methicillin-Resistant Staphylococcus aureus Infections

Pinho JO, Ferreira M, Coelho M, Pinto SN, Aguiar SI, Gaspar MM, 2024, Pharmaceuticals 17, 470.

ArticleEutectic Resolves Lysolipid Paradox in Thermoresponsive Liposomes

Eckhardt D, Semeraro EF, Steigenberger J, Schnur J, Kalie L, Massing U, Pabst G, Heerklotz H, 2024, Mol Pharm 21, 1768-1776.

ArticleReducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans

Sharifi S, Chaudhari P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M, 2024, Nat Commun 15, 1702

ArticleOral Delivery of the Vancomycin Derivative FU002 by a Surface-Modified Liposomal Nanocarrier

Werner J, Umstätter F, Hertlein T, Mühlberg E, Beijer B, Wohlfart S, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P, 2024, Adv Healthc Mater, e2303654.

ArticleSupramolecular dye nanoassemblies for advanced diagnostics and therapies

Ramezani P, De Smedt SC, Sauvage F, 2024, Bioeng Transl Med 9, e10652

ArticleImproved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier

Werner J, Umstätter F, Hertlein T, Beijer B, Kleist C, Mühlberg E, Zimmermann S, Haberkorn U, Ohlsen K, Fricker G, Mier W, Uhl P, 2024, Nanomedicine: Nanotechnology, Biology and Medicine, 102731.

ArticleMonolayer/Bilayer Equilibrium of Phospholipids in Gel or Liquid States: Interfacial Adsorption via Monomer or Liposome Diffusion?

Ullmann K, Fachet L, Nirschl H, Leneweit G, 2023, Gels 9, 803.

ArticleBrain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms of Parkinson’s Disease

Sela M, Poley M, Mora-Raimundo P, Kagan S, Avital A, Kaduri M, Chen G, Adir O, Rozencweig A, Weiss Y, Sade O, Leichtmann-Bardoogo Y, Simchi L, Age-Mizrachi S, Bell B, Yeretz-Peretz Y, Or AZ, Choudhary A, Rosh I, Cordeiro D, Choen-Adiv S, Berdichevsky Y, Ode A, Shklover J, Shainsky-Roitman J, Schroeder JE, Hershkovitz D, Hasson P, Ashkenazi A, Stern S, Laviv T, Ben-Zvi A, Avital A, Ashery U, Maoz BM, Schroeder A, 2023, Adv. Mater., e2304654.

ArticleA step forward on the in vitro and in vivo assessment of a novel nanomedicine against melanoma

Pinho JO, Matias M, Godinho-Santos A, Amaral JD, Mendes E, Perry MJ, Francisco AP, Rodrigues CMP, Gaspar MM, 2023. Int. J. Pharm. 640, 123011.

ArticleA mucoadhesive patch loaded with freeze-dried liposomes for the local treatment of oral tumors

Habib L, Alyan M, Ghantous Y, Shklover J, Shainsky J, Abu El-Naaj I, Bianco-Peled H, Schroeder A, 2023. Drug Delivery Transl. Res. 13, 1228-1245.

ArticleA Novel Approach for the Treatment of Aerobic Vaginitis: Azithromycin Liposomes-in-Chitosan Hydrogel

Čačić A, Amidžić Klarić D, Keser S, Radiković M, Rukavina Z, Jøraholmen MW, Uzelac L, Kralj M, Škalko-Basnet N, Šegvić Klarić M, Vanić Ž, 2023. Pharmaceutics 15, 1356.

ArticleInteraction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): a novel approach for stability assessment of oral drug carriers

Bohsen MS, Tychsen ST, Kadhim AAH, Grohganz H, Treusch AH, Brandl M, 2023. Eur. J. Pharm. Sci., 106384.

ArticleEstablishing a simple perfusion cell culture system for light-activated liposomes

Mäki-Mikola E, Lauren P, Uema N, Kikuchi K, Takashima Y, Laaksonen T, Lajunen T, 2023. Sci. Rep. 13, 2050.

ArticleQuantification of particle number concentration in liposomal suspensions by Laser Transmission Spectroscopy (LTS)

Sennato S, Sarra A, Capria CP, Bombelli C, Donati E, Postorino P, Bordi F, 2023. Colloids Surf. B 222, 113137.

ArticlePreclinical validation of a new hybrid molecule loaded in liposomes for melanoma management

Pinho JO, Matias M, Marques V, Eleutério C, Fernandes C, Gano L, Amaral JD, Mendes E, Perry MJ, Moreira JN, Storm G, Francisco AP, Rodrigues CMP, Gaspar MM, 2023. Biomed. Pharmacother. 157, 114021.

ArticleExtending the Pseudo-Phase Model of Detergent-Lipid Dispersions by a Detergent-Binding Protein

Vormittag LC, Heerklotz H, 2022. Langmuir, published online.

ArticleQuantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma

Dzhumashev D, Timpanaro A, Ali S, De Micheli AJ, Mamchaoui K, Cascone I, Rössler J, Bernasconi M, 2022, Cancers (Basel) 14

ArticleProbing Neuropeptide Volume Transmission In Vivo by Simultaneous Near-Infrared Light-Triggered Release and Optical Sensing

Xiong H, Lacin E, Ouyang H, Naik A, Xu X, Xie C, Youn J, Wilson BA, Kumar K, Kern T, Aisenberg E, Kircher D, Li X, Zasadzinski JA, Mateo C, Kleinfeld D, Hrabetova S, Slesinger PA, Qin Z, 2022. Angew. Chem. Int. Ed. 61, e202206122.

ArticleCancer immune therapy using engineered ‛tail-flipping’ nanoliposomes targeting alternatively activated macrophages

Kuninty PR, Binnemars-Postma K, Jarray A, Pednekar KP, Heinrich MA, Pijffers HJ, ten Hoopen H, Storm G, van Hoogevest P, den Otter WK, Prakash J, 2022. Nat. Commun. 13, 4548.

ArticleLiposomal sunitinib for ocular drug delivery: A potential treatment for choroidal neovascularization

Tavakoli S, Puranen J, Bahrpeyma S, Lautala VE, Karumo S, Lajunen T, Del Amo EM, Ruponen M, Urtti A, 2022. Int. J. Pharm. 620, 121725.

ArticleGenerating Large Numbers of Pancreatic Microtumors on Alginate-Gelatin Hydrogels for Quantitative Imaging of Tumor Growth and Photodynamic Therapy Optimization

Carigga Gutierrez NM, Le Clainche T, Coll JL, Sancey L, Broekgaarden M, 2022. Methods Mol. Biol. 2451, 91-105.

ArticleSynthetic cells with self-activating optogenetic proteins communicate with natural cells

Adir O, Albalak MR, Abel R, Weiss LE, Chen G, Gruber A, Staufer O, Kurman Y, Kaminer I, Shklover J, Shainsky-Roitman J, Platzman I, Gepstein L, Shechtman Y, Horwitz BA, Schroeder A, 2022. Nat. Commun. 13, 2328.

ArticleLung targeted liposomes for treating ARDS

Arber Raviv S, Alyan M, Egorov E, Zano A, Harush MY, Pieters C, Korach-Rechtman H, Saadya A, Kaneti G, Nudelman I, Farkash S, Flikshtain OD, Mekies LN, Koren L, Gal Y, Dor E, Shainsky J, Shklover J, Adir Y, Schroeder A, 2022. J. Controlled Release 346, 421-433.

ArticleIncorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses

Nijen Twilhaar MK, Czentner L, Bouma RG, Olesek K, Grabowska J, Wang AZ, Affandi AJ, Belt SC, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan JMM, 2022. Front. Immunol. 13, 842241.

ArticleImpact of Linker Modification and PEGylation of Vancomycin Conjugates on Structure-Activity Relationships and Pharmacokinetics

Umstätter F, Werner J, Zerlin L, Mühlberg E, Kleist C, Klika KD, Hertlein T, Beijer B, Domhan C, Zimmermann S, Ohlsen K, Haberkorn U, Mier W, Uhl P, 2022. Pharmaceuticals 15, 159.

ArticleOptimizing the Pharmacological and Optical Dosimetry for Photodynamic Therapy with Methylene Blue and Nanoliposomal Benzoporphyrin on Pancreatic Cancer Spheroids

Le Clainche T, Carigga Gutierrez NM, Pujol-Solé N, Coll J-L, Broekgaarden M, 2022 . Onco 2, 19-33.

ArticleQuercetin Liposomal Nanoformulation for Ischemia and Reperfusion Injury Treatment

Ferreira-Silva M, Faria-Silva C, Carvalheiro MC, Simões S, Marinho HS, Marcelino P, Campos MC, Metselaar JM, Fernandes E, Baptista PV, Fernandes AR, Corvo ML, 2022. Pharmaceutics 14, 194.

ArticleLiposomal Encapsulation Increases the Efficacy of Azithromycin against Chlamydia trachomatis

Bogdanov A, Janovák L, Vraneš J, Meštrović T, Ljubin-Sternak S, Cseh Z, Endrész V, Burián K, Vanić Ž, Virok DP, 2021, Pharmaceutics 14, 36.

ArticleLyophilization stabilizes clinical-stage core-crosslinked polymeric micelles to overcome cold chain supply challenges

Ojha T, Hu Q, Colombo C, Wit J, van Geijn M, van Steenbergen MJ, Bagheri M, Königs-Werner H, Buhl EM, Bansal R, Shi Y, Hennink WE, Storm G, Rijcken CJF, Lammers T, 2021, Biotechnol J 16, e2000212

ArticleRifampicin-Liposomes for Mycobacterium abscessus Infection Treatment: Intracellular Uptake and Antibacterial Activity Evaluation

Rinaldi F, Hanieh PN, Sennato S, De Santis F, Forte J, Fraziano M, Casciardi S, Marianecci C, Bordi F, Carafa M, 2021, Pharmaceutics 13

ArticleMembrane-water partitioning – Tackling the challenges of poorly soluble drugs using chaotropic co-solvents

Nasswetter LC, Fischer M, Scheidt HA, Heerklotz H, 2021. Biophys. Chem. 277, 106654.

ArticleMimicking Pathogens to Augment the Potency of Liposomal Cancer Vaccines

Nijen Twilhaar MK, Czentner L, van Nostrum CF, Storm G, den Haan JMM, 2021. Pharmaceutics 13, 954.

ArticleHow to Achieve High Encapsulation Efficiencies for Macromolecular and Sensitive APIs in Liposomes

Ullmann K, Leneweit G, Nirschl H, 2021. Pharmaceutics 13, 691.

ArticleEncapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions

Hettich BF, Bader JJ, Leroux JC, 2021. Adv. Healthc. Mater., e2100047.

ReviewLiposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance

Ferreira M, Ogren M, Dias JNR, Silva M, Gil S, Tavares L, Aires-da-Silva F, Gaspar MM, Aguiar SI, 2021. Molecules 26, 2047.

ReviewLiver-derived extracellular vesicles: A cell by cell overview to isolation and characterization practices

Zivko C, Fuhrmann G, Luciani P, 2021. Biochim. Biophys. Acta, Gen. Subj. 1865, 129559.

ReviewLiposomal Nanosystems in Rheumatoid Arthritis

Ferreira-Silva M, Faria-Silva C, Viana Baptista P, Fernandes E, Ramos Fernandes A, Corvo ML, 2021. Pharmaceutics 13, 454.

ArticleLiposome induction of CD8(+) T cell responses depends on CD169(+) macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion

Grabowska J, Affandi AJ, van Dinther D, Nijen Twilhaar MK, Olesek K, Hoogterp L, Ambrosini M, Heijnen DAM, Klaase L, Hidalgo A, Asano K, Crocker PR, Storm G, van Kooyk Y, den Haan JMM, 2021. J. Controlled Release 331, 309-320.

ArticleTowards the Development of Long Circulating Phosphatidylserine (PS)- and Phosphatidylglycerol (PG)-Enriched Anti-Inflammatory Liposomes: Is PEGylation Effective?

Klein ME, Rieckmann M, Sedding D, Hause G, Meister A, Mäder K, Lucas H, 2021. Pharmaceutics 13, 282.

ArticleLiposomal Nanovaccine Containing α-Galactosylceramide and Ganglioside GM3 Stimulates Robust CD8(+) T Cell Responses via CD169(+) Macrophages and cDC1

Grabowska J, Stolk DA, Nijen Twilhaar MK, Ambrosini M, Storm G, van der Vliet HJ, de Gruijl TD, van Kooyk Y, den Haan JMM, 2021. Vaccines (Basel) 9, 56.

ArticleAnalytical profiling and stability evaluation of liposomal drug delivery systems: a rapid UHPLC-CAD-based approach for phospholipids in research and quality control

Weber F, Rahnfeld L, Luciani P, 2020. Talanta 220, 121320.

ArticleOptimization of Liposomes for Antigen Targeting to Splenic CD169(+) Macrophages

Nijen Twilhaar MK, Czentner L, Grabowska J, Affandi AJ, Lau CYJ, Olesek K, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan J, 2020. Pharmaceutics 12, 1138.

ArticleSelective tumor antigen vaccine delivery to human CD169(+) antigen-presenting cells using ganglioside-liposomes

Affandi AJ, Grabowska J, Olesek K, Lopez Venegas M, Barbaria A, Rodríguez E, Mulder PPG, Pijffers HJ, Ambrosini M, Kalay H, O’Toole T, Zwart ES, Kazemier G, Nazmi K, Bikker FJ, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Storm G, van Kooyk Y, den Haan JMM, 2020. Proc. Natl. Acad. Sci. U. S. A. 117, 27528-27539.

ArticleIntegral Representation of Electrostatic Interactions inside a Lipid Membrane

Bossa GV, May S, 2020, Molecules 25

ArticleSpontaneous In Situ Formation of Liposomes from Inert Porous Microparticles for Oral Drug Delivery

Farzan M, Quebatte G, Strittmatter K, Hilty FM, Schoelkopf J, Huwyler J, Puchkov M, 2020. Pharmaceutics 12, 777.

ArticleLight-Activated Liposomes Coated with Hyaluronic Acid as a Potential Drug Delivery System

Kari OK, Tavakoli S, Parkkila P, Baan S, Savolainen R, Ruoslahti T, Johansson NG, Ndika J, Alenius H, Viitala T, Urtti A, Lajunen T, 2020. Pharmaceutics 12, 763.

ArticleSynthesis and aggregation behaviour of single-chain, 1,32-alkyl-branched bis(phosphocholines) – part 2: lateral chain length triggers self-assembling from sheets to fibres to vesicles

Gruhle K, Tuchtenhagen M, Müller S, Hause G, Meister A, Drescher S, 2020. Org. Biomol. Chem. 18, 3585-3598.

ArticleUltrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

de Matos MBC, Deckers R, van Elburg B, Lajoinie G, de Miranda BS, Versluis M, Schiffelers R, Kok RJ, 2019. Front. Pharmacol. 10, 1463.

ArticleBolalipid-Doped Liposomes: Can Bolalipids Increase the Integrity of Liposomes Exposed to Gastrointestinal Fluids?

Müller S, Gruhle K, Meister A, Hause G, Drescher S, 2019. Pharmaceutics 11, 646.

ArticlePhosphatidylserine (PS) and phosphatidylglycerol (PG) nanodispersions as potential anti-inflammatory therapeutics: Comparison of in vitro activity and impact of pegylation

Klein ME, Mauch S, Rieckmann M, Martinez DG, Hause G, Noutsias M, Hofmann U, Lucas H, Meister A, Ramos G, Loppnow H, Mäder K, 2020. Nanomedicine 23, 102096.

ArticleAzithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections

Vanić Ž, Rukavina Z, Manner S, Fallarero A, Uzelac L, Kralj M, Amidžić Klarić D, Bogdanov A, Raffai T, Virok DP, Filipović-Grčić J, Škalko-Basnet N, 2019. Int. J. Nanomed. 14, 5957-5976.

ArticleTailoring the lipid composition of nanoparticles modulates their cellular uptake and affects the viability of triple negative breast cancer cells

Abumanhal-Masarweh H, da Silva D, Poley M, Zinger A, Goldman E, Krinsky N, Kleiner R, Shenbach G, Schroeder JE, Shklover J, Shainsky-Roitman J, Schroeder A, 2019. J. Controlled Release 307, 331-341.

ArticleSodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin

Abumanhal-Masarweh H, Koren L, Zinger A, Yaari Z, Krinsky N, Kaneti G, Dahan N, Lupu-Haber Y, Suss-Toby E, Weiss-Messer E, Schlesinger-Laufer M, Shainsky-Roitman J, Schroeder A, 2019. J. Controlled Release 296, 1-13.

ArticleMixing behaviour of bilayer-forming phosphatidylcholines with single-chain alkyl-branched bolalipids: effect of lateral chain length

Müller S, Kind M, Gruhle K, Hause G, Meister A, Drescher S, 2019. Biophys. Chem. 244, 1-10.

ArticleThermosensitive liposomes for triggered release of cytotoxic proteins

de Matos MBC, Beztsinna N, Heyder C, Fens M, Mastrobattista E, Schiffelers RM, Leneweit G, Kok RJ, 2018. Eur. J. Pharm. Biopharm. 132, 211-221.

ArticleMixing behaviour of asymmetrical glycerol diether bolalipids with saturated and unsaturated phosphatidylcholines

Müller S, Meister A, Otto C, Hause G, Drescher S, 2018. Biophys. Chem. 238, 39-48.

ArticleInvestigations of the influence of liposome composition on vesicle stability and drug transfer in human plasma: a transfer study

Holzschuh S, Kaess K, Bossa GV, Decker C, Fahr A, May S, 2018. J. Liposome Res. 28, 22-34.

ArticleStudy on the in situ aggregation of liposomes with negatively charged phospholipids for use as injectable depot formulation

Rahnfeld L, Thamm J, Steiniger F, van Hoogevest P, Luciani P, 2018. Colloids Surf. B 168, 10-17.

ArticleUltrafast Near-Infrared Light-triggered Intracellular Uncaging to Probe Cell Signaling

Li X, Che Z, Mazhar K, Price TJ, Qin Z, 2017. Adv. Funct. Mater. 27.