Webinar January 2026 – Dr. Jacobsen

On Wednesday, January 14, 2026, an online seminar on "Phospholipids used for in vitro biopharmaceutical characterization of oral drugs" will be held at 3.30 p.m. (CET).

The speaker will be Dr. Ann-Christin Jacobsen from Kiel University, Germany.

Here you can register to the webinar.

Abstract

Phospholipids are important parts of many in vitro assays for biopharmaceutical characterization of oral drugs and dosage forms. These include dissolution, permeation, and combined dissolution-permeation assays. Here, phospholipids serve different functions with a common aim: increasing bio-relevance.

In dissolution assays phospholipids are increasingly common constituents of the dissolution medium to mimic the gastrointestinal fluids. In the webinar, I will briefly present different variants of simulated intestinal fluids for dissolution testing. Based on examples, I will discuss the impact of simulated intestinal fluids on dissolution results.

In permeation assays phospholipids are constituents of the permeation barrier itself. As main constituent of cell membranes, phospholipids naturally occur in cell-based and tissue-based permeation assays. The webinar, however, focuses on artificial permeation barriers containing phospholipids. These include the parallel artificial membrane permeability assay (PAMPA), the phospholipid vesicle permeability assay (PVPA), and the Permeapad® barrier. In the webinar, I will briefly present the structure of those artificial barriers. Based on examples, I will discuss the impact of the phospholipid composition of the artificial barriers on the permeation results.

Here you can register to the webinar.