Workshop on Phospholipids as an important determinant of oral drug absorption

The Phospholipid Research Center and The International Association for Pharmaceutical Technology (APV) organize a workshop on phospholipids, an important determinant of oral drug absorption.

  • How important are they for a successful development of biorelevant in vitro dissolution and permeation assays?
  • How can they be used in formulation development to improve the oral bioavailability of drugs?

Program & Registration

The workshop starts on Tuesday (June 20, 2023) at 10:00 a.m. (CEST) and will conclude on Wednesday (June 21, 2023) at 1:00 p.m.

Here you can download the program and registration form.


Quality Hotel View
Hyllie stationstorg 29
SE-215 32 Malmö, Sweden


Phospholipids are excipients of natural origin that play several roles in the oral administration of drugs. With the growing number of drugs with poor water solubility, there is an increasing need for new formulation concepts that ensure effective dissolution or solubilization of these drugs in the gastrointestinal tract. At this point, phospholipids represent interesting excipient candidates for e.g. lipid-based, co-amorphous or micellar formulations. When it comes to best predicting the in vivo drug release of poorly soluble drug candidates based on in vitro release assays, phospholipids come back into play. Together with other physiologically relevant components, such as bile salts, their use in biorelevant dissolution media usually allows a much better prediction of the in vivo release of poorly soluble drugs from their formulations. Finally, phospholipids also play a major role in drug absorption. As important cell membrane components, they are key determinants of the permeability of the gastrointestinal mucosa and therefore also influence the fraction of the orally administered drug dose that ultimately reaches the systemic circulation.

The aim of the workshop is to provide the participants with the latest knowledge on current phospholipid-based formulation concepts for small molecules and biological agents as well as on advanced and predictive in vitro methods for characterization of drug release and permeation.


Tuesday, June 20

PD Dr. habil. Simon Drescher (PRC Heidelberg, Germany) - Introduction in the use of phospholipids in pharmaceutical formulations

Prof. Dr. Sandra Klein (University of Greifswald, Germany) - The role of phospholipids in the development of in vitro assays to predict in vivo drug release

Prof. Dr. Anette Müllertz (University of Copenhagen, Denmark) - Phospholipid complexes in SNEDDS for increasing gastro-intestinal absorption of peptides

Dr. Paulina Skupin-Mrugalska (Poznan University of Medical Sciences, Poland) - Phospholipid/polymer mixtures as matrices for solid dispersions of poorly soluble drugs

Prof. Dr. Thomas Rades (University of Copenhagen) - Co-amorphous phospholipid drug complexes

Dr. Frank Karkossa (University of Greifswald, Germany) - Oral mixed micelle formulations—a novel phospholipid-based platform for safe and effective pediatric drug delivery

Wednesday, June 21

N.N. - Natural phospholipids as pharmaceutical excipients − experiences from the pharmaceutical industry

Dr. Ann-Christin Jacobsen (Uppsala University, Sweden) - Phospholipids may boost or depress drug absorption: how to get the balance right

Dr. Meike van der Zande (Wageningen University, The Netherlands) - Evaluation of the properties of phospholipid-based nanocarriers for oral delivery using an in vitro test strategy

Prof. Dr. Martin Brandl (University of Southern Denmark, Odense, Denmark) - Latest additions to the in vitro toolbox for biopharmaceutical evaluation of enabling formulations